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Mar17
Advexin® Passes Phase I/II Clinical Trial in Advanced Esophageal Cancer Patients

Intratumoral administration of multiple Advexin® doses in advanced esophageal cancer patients has shown to be safe, feasible and clinically active; giving Introgen Therapeutics, Inc. enough reason to announce the publication of the positive data from the said Phase I/II clinical trial of Advexin®.

Advexin® is an investigational cancer therapy that utilizes an adenoviral vector to deliver the p53 tumor suppressor directly to tumors. Collaborators of Introgen from Chiba University in conducted the trial, and the data appears in the current issue of Cancer Science.

"Refractory esophageal cancer is a highly malignant disease, for which novel therapies are required," said Robert E. Sobol, M.D., senior vice president, Medical and Scientific Affairs, at Introgen. "Even in this difficult-to-treat population, ADVEXIN demonstrated clinical activity providing local tumor control without adding significant toxicities."

Read more at Introgen Therapeutics, Inc. News.

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