Findings appearing in the May 3 issue of the European Journal of Cancer states that a molecule that interferes with the internal scaffolding that shapes the cell may kill cancer cells, retard the growth of tumors and give a boost to a common chemotherapy drug: etoposide.
The researchers found that ML-7, which inhibits an enzyme called myosin light chain kinase, which is important to the structure and dynamics of the cytoskeleton, induces cell suicide, or apoptosis, in cultured breast and prostate cancer cell lines. In addition, treatment with ML-7 in combination with etoposide, a chemotherapy drug used to treat solid tumors, enhanced the ability of etoposide to kill cancer cells. Read more at UIC News Release.
The study suggests an entirely new target in cancer treatment.
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