A research team led by Pappachan Kolattukudy, dean of the UCF Burnett College of Biomedical Sciences, found that the levels of MCPIP increased in mice as their blood vessels became inflamed and heart disease began to develop. The formation of MCPIP leads to the death of healthy cells, so treatments that block that formation could prove effective for heart disease. The researchers are trying to discover the molecular changes that occur as heart disease develops. Better understanding those molecular changes would help with the development of drugs that can either prevent or treat the disease.
The research study which was funded through a $1.4 million grant from the National Institutes of Health is published at the May 12 issue of Circulation Research, the American Heart Association journal.
Read more at UCF News.
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