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Jun29
Anadys Pharma Suspended Dosing of HCV in ANA975 Phase 1b Clinical Trial
In its ongoing Phase 1b clinical trial with ANA975, Anadys Pharmaceuticals, Inc. suspended the dosing of Hepatitis C virus (HCV) in patients in lieu of pending additional analysis of recently obtained information from pre-clinical 13-week toxicology studies in animals.
"Although we have not seen any serious adverse events in clinical experience with ANA975, the health and safety of patients are our first and overriding concern," said Kleanthis G. Xanthopoulos, Ph.D., Anadys' President and CEO. "Consequently, we are suspending this trial for appropriate reasons of precaution while we gain a greater understanding of this recently obtained information."

The new data preliminarily shows intense immune stimulation in animals as side effect. Anadys and Novartis (its collaborator) are now in the process of evaluating these observations in order to determine their next move.

The two companies believe that ANA975 is an effective immunomodulator and therefore a potentially promising agent for patients infected with hepatitis C virus and can’t wait to continue with the program.

Read the full press release.

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