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Jun13
Panacos Initiates Phase IIb Clinical Trial of HIV Drug Candidate Bevirimat (PA-457)
Panacos Pharmaceuticals, Inc. will commence Phase IIb clinical trials of bevirimat (previously designated PA-457) for the treatment of HIV.Bevirimatbelongs to a new class of oral anti-HIV called maturation inhibitors.
"With the benefit of the results of our Phase 2a study, we have been able to focus on a dose range that we believe will provide maximum antiviral benefit to patients. In the Phase 2b trial, we plan to test these doses of bevirimat in combination with approved HIV drugs as part of an optimized regimen in patients failing treatment due to drug resistance. The goal of this study is to select the most appropriate dose to take into pivotal Phase 3 testing."
About 40 HIV-infected patients will be enrolled in the study to test the efficacy of three dosages: 400mg, 500mg and 600mg. Other details of the study design were indicated in Panacos' press release.

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« Imatinib (commercial name: Gleevec) Attacks Prostate Cancer by Cutting off Blood Supply in Mouse Model | Main | FDA Grants Priority Review to Amgen's Biologic License Application for Panitumumab »

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