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Nov22
Artemis Agreed With Merck & Co., Inc. In making Genetically Engineered In-Vivo RNAi Mouse Models

The Cologne-based Artemis Pharmaceuticals GmbH entered into a research agreement with Merck & Co., Inc. (NYSE: MRK) for the construction of a large number of shRNA interference ("shRNAi ") - genetically engineered mouse models for the in vivo functional analysis of selected disease related genes.

RNAi.jpg The terms of agreement include:

  • Artemis generating a genetically engineered shRNAi "knock down" mouse models for Merck using Artemis' proprietary, optimized and fully integrated vector construction, ES cell transfection and inducible RNAi technology.
  • Merck providing selected shRNA sequences that correspond to mouse genes that may also play a central role in human diseases.
  • Artemis using its technologies to achieve constitutive as well as inducible functional down-regulation of the expression of the gene targets provided by Merck.
  • Artemis Pharmaceuticals has been able to develop the worldwide leading portfolio of scientific and technological tools in murine molecular genetics and functional genomics, offering custom-made genetically engineered mouse models for use at various stages of the industrial drug discovery process or for academic research.

    Find more details from the press release.

    [Photo Credit: RNA Network]


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