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Nov 5
CuraGen and TopoTarget Out-Licensed Worldwide Rights of PXD118490 (Preclinical HDAC Inhibitor) To LEO Pharma

One of the world's leading companies in dermatology, LEO Pharma, has been granted the exclusive worldwide rights to develop, manufacture, and commercialize a novel preclinical HDAC inhibitor - PXD118490 – for the treatment of psoriasis and other dermatological disorders.

This development was recently announced by CuraGen Corporation (Nasdaq: CRGN) and TopoTarget A/S (CPH: TOPO).

Curagen.jpgThe terms of agreement include the following:

Between TopoTarget and LEO Pharma,

  • TopoTarget will receive initial payments totaling 2,000,000 euros (approximately US$2.6 million).
  • TopoTarget is eligible to receive additional milestone payments of up to 32,000,000 euros (approximately US$40.8 million), and tiered royalties on any future product sales.
  • Between CuraGen and TopoTarget (existing terms of agreement),

  • CuraGen will receive 50% of all payments received by TopoTarget under the licensing agreement between TopoTarget and LEO Pharma.
  • Find more details from the press release

    [Photo Credit: Curagen Corp.]


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