Both primary and secondary endpoints in the Hypnion’s initial Phase II clinical trial evaluating HY10275 at doses of 1 mg and 3 mg in adults with transient insomnia have been reached.
HY10275 is a proprietary compound discovered and developed by Hypnion as a dual-acting H1 / 5HT2a compound using the SCORE-2004™ technology.
HY10275 is a novel compound highly selective for histamine H1 and serotonin 5HT2a, two chemical receptors that are known to impact the ability to fall asleep and stay asleep.
In the Phase II trial, HY10275 demonstrated statistically significant improvements in Wake After Sleep Onset (WASO), an objective measure of sleep maintenance, and with no adverse effects.
Find more details from the press release.
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