Analyses of interim antibody data indicate that patients treated with 900 mg or 300 mg per week doses of Riquent had greater reductions in antibodies to double-stranded DNA (dsDNA) than patients treated with
100 mg per week or placebo.
The results showed a significant dose response when comparing all Riquent-treated patients to placebo-treated patients (p < 0.0001), and each Riquent dose group to the placebo dose group (p < 0.0015 for 100 mg, p < 0.0001 for 300 mg and 900 mg).
Riquent® (abetimus sodium) is La Jolla Pharmaceutical Company’s drug candidate for systemic lupus erythematosus (lupus or SLE) - a chronic, potentially life-threatening autoimmune disease.
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