GlaxoSmithKline (NYSE: GSK)’s investigational once daily extended release formulation of Lamictal® (lamotrigine) - Lamictal® XR™ - has been found effective as add-on treatment in patients with partial epilepsy with and without secondary generalization.
Currently, Lamictal® XR™ is being developed for the treatment of epilepsy and once approved will become the first extended release, new generation epilepsy treatment taken once-daily.
The finding abovementioned was derived from data of two clinical trials recently presented at the American Academy of Neurology (AAN) meeting.
According to Dean Naritoku, M.D., Professor of Neurology and Pharmacology, Southern Illinois University, Springfield, IL.:
"These data are important because they show that the extended release formulation of Lamictal reduces the frequency of seizures. The once daily dosing regimen may also provide a more convenient treatment option for patients.
In addition, when compared to Lamictal immediate release, given twice a day, the new investigational formulation demonstrated fewer daily fluctuations in serum concentration and more stable blood levels over time."
Being suffered by more than three million Americans of all ages (according to the Epilepsy Foundation), epilepsy is defined by recurrent unprovoked seizures and is a change in sensation, awareness, or behavior brought about by an electrical disturbance in the brain.
Read the full report.
My name is Denise Simon and i would like to show you my personal experience with Lamictal.
I am 57 years old. Have been on Lamictal for 24 weeks now. Lamictal has worked well with no side effects other than the sleep problesm. My problems with other meds included constipation and depression. Lamictal also relieves my anger bouts...and settles me down which probably helps with seizure control.
I have experienced some of these side effects-
Following conversion from tegretol and Zonegran, I began on 400 mg Lamictal. Bad dreams followed with sleep talking and thrashing during dreams. This turned into more vivid short dreams in which I could not discern dreams from reality. I have contacted my Dr asking permission to take the meds earlier and he concurred to try them 4 hrs earlier. HE is leaning toward changing the meds. After laying out a lot of $ for a 3 month supply, I am reluctant to change meds as I am tight on $....
I hope this information will be useful to others,
Denise Simon
Posted by: Lamicta Prescription Medication | November 3, 2008 12:46 PM | Permalink to Comment